P A Charlton Selected Research

XR5944

2/2005	Antitumour activity of XR5944 in vitro and in vivo in combination with 5-fluorouracil and irinotecan in colon cancer cell lines.
4/2001	Antitumor activity of XR5944, a novel and potent topoisomerase poison.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

P A Charlton Research Topics

Disease

7	Neoplasms (Cancer) 01/2013 - 01/2000
2	Carcinoma (Carcinomatosis) 02/2005 - 04/2001
2	Melanoma (Melanoma, Malignant) 07/2000 - 01/2000
1	Adenocarcinoma 12/2012
1	Pancreatic Neoplasms (Pancreatic Cancer) 12/2012
1	Hypoxia (Hypoxemia) 07/2012
1	Ataxia Telangiectasia (Louis Bar Syndrome) 07/2012
1	Colonic Neoplasms (Colon Cancer) 02/2005
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/2001
1	Rickets (Rachitis) 08/2000
1	Ovarian Neoplasms (Ovarian Cancer) 07/2000
1	Fibrosarcoma 01/2000

Drug/Important Bio-Agent (IBA)

2	XR5944IBA 02/2005 - 04/2001
2	Irinotecan (Camptosar)FDA LinkGeneric 02/2005 - 04/2001
1	Small Interfering RNA (siRNA)IBA 01/2013
1	Choline KinaseIBA 01/2013
1	Proteins (Proteins, Gene)FDA Link 01/2013
1	Gemcitabine FDA Link 12/2012
1	berzosertibIBA 12/2012
1	3- amino- 6- (4- (methylsulfonyl)phenyl)- N- phenylpyrazine- 2- carboxamideIBA 07/2012
1	Oxygen (Dioxygen)IBA 07/2012
1	Phosphotransferases (Kinase)IBA 07/2012
1	Protein Kinases (Protein Kinase)IBA 06/2007
1	tozasertibIBA 06/2007
1	Fluorouracil (Carac)FDA LinkGeneric 02/2005
1	CamptothecinIBA 04/2001
1	Topotecan (Hycamtin)FDA LinkGeneric 04/2001
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 04/2001
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 04/2001
1	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2001
1	Etoposide (VP 16)FDA LinkGeneric 04/2001
1	6- ((2- (dimethylamino)ethyl)amino)- 3- hydroxy- 7H- indeno(2,1- c)quinolin- 7- oneIBA 04/2001
1	25-hydroxyvitamin DIBA 08/2000
1	Alkaline PhosphataseIBA 08/2000
1	Phosphorus (Red Phosphorus)IBA 08/2000
1	CalciumIBA 08/2000
1	Vitamin D FDA LinkGeneric 08/2000
1	Topoisomerase InhibitorsIBA 07/2000
1	acridine DACAIBA 07/2000
1	Cisplatin (Platino)FDA LinkGeneric 07/2000
1	Paclitaxel (Taxol)FDA LinkGeneric 07/2000
1	treosulfanIBA 07/2000
1	Adenosine Triphosphate (ATP)IBA 07/2000
1	AntibodiesIBA 01/2000
1	Antifibrinolytic Agents (Antifibrinolytics)IBA 01/2000
1	Aprotinin (Trasylol)FDA Link 01/2000
1	Plasminogen Activator Inhibitor 1IBA 01/2000
1	VitronectinIBA 01/2000
1	Monoclonal AntibodiesIBA 01/2000

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 12/2012 - 04/2001
1	Chemoradiotherapy 12/2012
1	Therapeutics 12/2012
1	Radiotherapy 07/2012